chemical structures ( identified by Roman Numerals in previous list)


Wednesday, February 1, 2017
CHEMICALS FROM GREWIA-1
G. asiatica
Flowers
Flavonoids: quercetin (I), quercetin-3-O-ß-D-glucoside, naringenin (II) and naringenin-7-O-ß-D-glucoside ; grewinol (III), 3,21,24-trimethyl-5,7-dihydroxyhentriacontanoic acid d-lactone (IV) and ß-sitosterol
Fruits
Flavonoids: quercetin (I), quercetin-3-O-ß-D-glucoside and naringenin-7-O-ß-D-glucoside; anthocyanins: pelargonidin-3,5-diglucoside (V), delphinidin-3-glucoside (VI) and cyanidin-3-glucoside (VII); and catechin (VIII)
Leaves
Flavonoids: quercetin (I) and kaempferol (IX) and their glucosides
Stem
Triterpenoids: taraxerol, erythrodiol (X), lupeol (XI), betulin (XII), lupenone, friedelin (XIII) and ß-amyrin; ß-sitosterol
G. bicolor
Whole plant
Triterpenoids: lupeol (XI) and betulin (XII) ; ß-sitosterol and ß-sitosterol-3-O-glucoside \
Alkaloids: Harman (XIV), 6-methoxyharman (XV) and 6-hydroxyharman (XVI)
G. bilamellata
Aerial parts
Coumarinolignans: grewin(XVII) and cleomiscosin D(XVIII); neolignans: nitidine(XIX) and bilagrewine(XX); triterpenoids: 3a,20-lupanediol (XXI) and 2a-3ß-dihydroxy-olean-12-en-28-oic acid(XXII); pyran derivative: icariol A2; sterol: daucosterol; 8-O-4’-neolignanguaiacylglycerol-ß-coniferyl ether; 2,6-dimethoxy-1-acetonylquinol(XXIII) and ciwujiatone(XXIV)
G. elyseoi
Stem bark
coumarinolignan : grewine(XVII)
G. flavescens
Roots
Triterpenoids: a-amyrin, ß-amyrin, betulin(XII) and friedelin(XIII); triacontanol and ß-sitosterol
Stem bark
Triterpenoids: a-amyrin, ß-amyrin and erythrodiol(X); ß-sitosterol
G. mollis
Aerial parts
Flavonoids: Luteloin (XXV), 7-(1-O-ß-D-galacturonide)-4’-(1-O- ß-glucopyranosyl)-3’4’,5,7-Tetrahydroxyflavone (XXVI),
Triterpenoids: 7ß-hydroxy-23-ene-deoxojessic acid (XXVII), 7ß-hydroxy-23- deoxojessic acid (XXVIII),
Steroids: ß-Sitosterol, ß-Sitosterol-3-O-glucoside (XXIX).
G. rothi
Root bark
Triterpenoid: lupeol(XI); leucoanthocyanidin(XXX)
G. tenax syn. G. populifolia
Leaves
Triacontanol, tetratriacont-21-ol-12-one and ß-sitosterol
Seeds
Sterols: sitosterol and stigmasterol(XXXI)
Stem bark
Triterpenoids: a-amyrin, ß-amyrin, lupenone, erythrodiol(X) and betulin(XII); ß-sitosterol and triacontanol
G. tiliaefolia
Roots
Triterpenoids: lupeol(XI) and friedelin(XIII)
Stem bark
Triterpenoids: lupeol(XI), betulin(XII) and friedelin(XIII)
G. tomentosa
Whole plant
Tiliroside(XXXII) and luteolin(XXXIII)
REFERENCES
Flowers
Flavonoids: quercetin (I), quercetin-3-O-ß-D-glucoside, naringenin (II) and naringenin-7-O-ß-D-glucoside ; grewinol (III), 3,21,24-trimethyl-5,7-dihydroxyhentriacontanoic acid d-lactone (IV) and ß-sitosterol
Fruits
Flavonoids: quercetin (I), quercetin-3-O-ß-D-glucoside and naringenin-7-O-ß-D-glucoside; anthocyanins: pelargonidin-3,5-diglucoside (V), delphinidin-3-glucoside (VI) and cyanidin-3-glucoside (VII); and catechin (VIII)
Leaves
Flavonoids: quercetin (I) and kaempferol (IX) and their glucosides
Stem
Triterpenoids: taraxerol, erythrodiol (X), lupeol (XI), betulin (XII), lupenone, friedelin (XIII) and ß-amyrin; ß-sitosterol
G. bicolor
Whole plant
Triterpenoids: lupeol (XI) and betulin (XII) ; ß-sitosterol and ß-sitosterol-3-O-glucoside \
Alkaloids: Harman (XIV), 6-methoxyharman (XV) and 6-hydroxyharman (XVI)
G. bilamellata
Aerial parts
Coumarinolignans: grewin(XVII) and cleomiscosin D(XVIII); neolignans: nitidine(XIX) and bilagrewine(XX); triterpenoids: 3a,20-lupanediol (XXI) and 2a-3ß-dihydroxy-olean-12-en-28-oic acid(XXII); pyran derivative: icariol A2; sterol: daucosterol; 8-O-4’-neolignanguaiacylglycerol-ß-coniferyl ether; 2,6-dimethoxy-1-acetonylquinol(XXIII) and ciwujiatone(XXIV)
G. elyseoi
Stem bark
coumarinolignan : grewine(XVII)
G. flavescens
Roots
Triterpenoids: a-amyrin, ß-amyrin, betulin(XII) and friedelin(XIII); triacontanol and ß-sitosterol
Stem bark
Triterpenoids: a-amyrin, ß-amyrin and erythrodiol(X); ß-sitosterol
G. mollis
Aerial parts
Flavonoids: Luteloin (XXV), 7-(1-O-ß-D-galacturonide)-4’-(1-O- ß-glucopyranosyl)-3’4’,5,7-Tetrahydroxyflavone (XXVI),
Triterpenoids: 7ß-hydroxy-23-ene-deoxojessic acid (XXVII), 7ß-hydroxy-23- deoxojessic acid (XXVIII),
Steroids: ß-Sitosterol, ß-Sitosterol-3-O-glucoside (XXIX).
G. rothi
Root bark
Triterpenoid: lupeol(XI); leucoanthocyanidin(XXX)
G. tenax syn. G. populifolia
Leaves
Triacontanol, tetratriacont-21-ol-12-one and ß-sitosterol
Seeds
Sterols: sitosterol and stigmasterol(XXXI)
Stem bark
Triterpenoids: a-amyrin, ß-amyrin, lupenone, erythrodiol(X) and betulin(XII); ß-sitosterol and triacontanol
G. tiliaefolia
Roots
Triterpenoids: lupeol(XI) and friedelin(XIII)
Stem bark
Triterpenoids: lupeol(XI), betulin(XII) and friedelin(XIII)
G. tomentosa
Whole plant
Tiliroside(XXXII) and luteolin(XXXIII)
REFERENCES
Goyal, Praveen Kumar. "Phytochemical and pharmacological properties of the genus Grewia: a review." International journal of pharmacy and pharmaceutical sciences 4.4 (2012): 72-78.
http://www.ijppsjournal.com/Vol4Suppl4/4772.pdf
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